Publications

Induction of cancer stem cells from mouse fibroblasts

Shabrish S, Naorem LD, Mohanty S, Kumar R, Lopes R, Akhter N, Khare NK, Joshi R, Sawant R, Raghuram GV, Jadhav V, Shinde S, Chandrani P, Mittra I

Sci Rep (2025)

Paper

Comprehensive Genomic Profiling of Anaplastic Thyroid Cancer Identifies Alterations in THRA, a Potential Modifier of Cellular Plasticity

Trivedi V, Noronha V, Bal M, Chandrani P, Poojary D, Saldanha E, Choughule A, Pange P, Gupta V, Menon N, Patil V, Shah M, Chaturvedi P, Prabhash K, Dutt A

JCO Glob Oncol (2025)

Paper

Assessment of plasma derived microbiome profiles in lung cancer using targeted and whole exome sequencing

Behel V, Hait S, Noronha V, Chowdhury A, Chandrani P, Patil V, Menon N, Mishra R, Bawaskar B, Dahimbekar G, Shah M, Kaushal R, Veldore V, Goswami H, Bharde A, Khandare J, Shafi G, Choughule A, Tyagi N, Desai S, Prabhash K, Dutt A

NPJ Syst Biol Appl (2025)

Paper

Genomic Profiling of Driver Gene Alterations in Patients With Non-Small Cell Lung Cancer, Patterns of Treatment and Impact on Survival Outcomes: A Single Center Experience of More Than 1200 Patients

Shah M, Noronha V, Patil V, Singh AK, Menon N, Goud S, Shah S, More S, Kapoor A, Mishra BK, Chandrani P, Chougule A, Gupta V, Pange P, Shetty O, Pai T, Kaushal R, Yadav S, Basu M, Vora D, Vaidyanathan A, Kumar P, Jacob R, Shah A, Pradhan RR, Samaddar D, Shenoy V, Singh B, Puviarasan R, Bagra S, Desai R, Saldanha E, Poojary D, Pathak A, Ray S, Bhardwaj H, Shetty U, Iyer R, Das R, Mer N, Shah H, Kaushal Y, Singh A, Panmand H, Gosavi G, Ubharay A, Iyer A, Turel U, Shetake A, Maske K, Janu A, Purandare N, Pawar A, Mandhania M, Prabhash K

Clin Lung Cancer (2025)

Paper

Genomic Characterization of Papillary Thyroid Cancer Reveals Germline Mutations Associated With Congenital Hypothyroidism

Trivedi V, Kore H, Poojary D, Noronha V, Bal M, Chandrani P, Choughule A, Pange P, Gupta V, Menon N, Patil V, Shah M, Chaturvedi P, Prabhash K, Dutt A

JCO Glob Oncol (2025)

Paper

The impact of co-occurring tumor suppressor mutations with mEGFR as early indicators of relapse in lung cancer

Hait S, Noronha V, Chowdhury A, Chaudhary A, Bawaskar B, Dahimbekar G, Ahmad S, Joshi A, Patil V, Menon N, Shah M, Kaushal R, Choughule A, Bharde A, Khandare J, Shafi G, Lakhwani D, Desai S, Chandrani P, Prabhash K, Dutt A

ESMO Open (2025)

Paper

Clinical characteristics and first-line palliative treatment patterns in 3,414 patients with advanced lung cancer in India

Trikha M, Noronha V, Shah M, Patil V, Menon N, Singh A, Chandrani P, Shetty O, Kaushal RK, Pai T, Janu A, Purandare N, Prabhash K

Ecancermedicalscience (2025)

Paper

Deep Diving Into the Fusion Across Cancer Types in the Indian Population From Formalin-Fixed Paraffin-Embedded RNA-Exome Data: A Road to Discovering Novel Rearrangements With Clinical Relevance

Khuntia SP, Mukherjee N, Javle V, Tanwar NA, Sreekanthreddy P, Varghese L, Gowda P, Kottlahouse A, Chandrani P, Choughule A, Pange P, Gupta V, Noronha V, Patil VM, Pramanik R, Kumar S, Nayak SP, Babu S, Shetty R, Kantharaju M, Chinder PS, Korlimarla A, Srinath BS, Prabhash K, Periyasamy G, Rishi KD, Goswami HM, Veldore VH

JCO Glob Oncol (2024)

Paper

Uniqueness of lung cancer in Southeast Asia

Noronha V, Budukh A, Chaturvedi P, Anne S, Punjabi A, Bhaskar M, Sahoo TP, Menon N, Shah M, Batra U, Nathany S, Kumar R, Shetty O, Ghodke TP, Mahajan A, Chakrabarty N, Hait S, Tripathi SC, Chougule A, Chandrani P, Tripathi VK, Jiwnani S, Tibdewal A, Maheshwari G, Kothari R, Patil VM, Bhat RS, Khanderia M, Mahajan V, Prakash R, Sharma S, Jabbar AA, Yadav BK, Uddin AFMK, Dutt A, Prabhash K

Lancet Reg Health Southeast Asia (2024)

Paper

RET Alterations Differentiate Molecular Profile of Medullary Thyroid Cancer

Prabhash K, Saldanha E, Patil V, Bal M, Reddy PS, Sanjeev A, Kumar R, Poojary D, Noronha V, Menon N, Mittal N, Trivedi V, Nambiar K, Mishra R, Tanwar N, Malhotra R, Pange P, Gupta V, Veldore VH, Chougule A, Chaturvedi P, Dutt A, Chandrani P

JCO Precis Oncol (2024)

Paper

Clinical characteristics, outcomes and prognostic factors in KRAS mutant lung cancers: experience from a tertiary care cancer center in India

Noronha V, Sarkar L, Patil V, Menon N, Shah M, Pawar A, Chowdhury OR, Shetty O, Chougule A, Chandrani P, Kaushal R, Pai T, Janu A, Chakrabarty N, Prabhash K

Ecancermedicalscience (2024)

Paper

Natural History of Germline BRCA1 Mutated and BRCA Wild-type Triple-negative Breast Cancer

Gardi N, Chaubal R, Parab P, Pachakar S, Kulkarni S, Shet T, Joshi S, Kembhavi Y, Chandrani P, Quist J, Kowtal P, Grigoriadis A, Sarin R, Govindarajan R, Gupta S

Cancer Res Commun (2024)

Paper

The Role of Systemic Therapy in Patients with Advanced Non-small Cell Lung Cancer and a Poor Eastern Cooperative Oncology Group Performance Status

Shah M, Noronha V, Patil V, Menon N, Singh AK, Shah A, Kumar P, Roychoudhary O, Peelay Z, Janu A, Purandare N, Chakrabarty N, Patil V, Kaushal R, Shetty O, Pai T, Chandrani P, Chougule A, Prabhash K

Clin Oncol (R Coll Radiol) (2024)

Paper

Whole exome sequencing uncovers HRAS mutations as potential mediators of resistance to metronomic chemotherapy

Sambath J, Noronha V, Manda SS, Mishra R, Chandrani P, Patil V, Menon N, Chougule A, Ramachandran V, Limaye S, Kuriakose MA, Banavali SD, Kumar P, Prabhash K

Gene (2024)

Paper

Association of Cutibacterium acnes with human thyroid cancer

Trivedi V, Noronha V, Sreekanthreddy P, Desai S, Poojary D, Varghese L, Gowda P, Butle A, Mishra R, Bal M, Mittal N, Rane S, Kane S, Basu S, Patil V, Menon N, Singh AK, Chaturvedi P, Chandrani P, Choughule A, Veldore V, Prabhash K, Dutt A

Front Endocrinol (Lausanne) (2023)

Paper

Real-World Evidence of EGFR Targeted Therapy in NSCLC- A Brief Report of Decade Long Single Center Experience

Chougule A, Chandrani P, Noronha V, Pange P, Kale S, Nikam A, Nambiar K, Marchande D, Durve A, Gupta V, Jagtap V, Tiwrekar P, Menon N, Joshi A, Kaushal R, Pai T, Patil VM, Dutt A, Banavali SD, Prabhash K

JTO Clin Res Rep (2023)

Paper

Understanding the Impact of Population and Cancer Type on Tumor Mutation Burden Scores: A Comprehensive Whole-Exome Study in Cancer Patients From India

Tanwar NA, Malhotra R, Satheesh AP, Khuntia SP, Sreekanthreddy P, Varghese L, Kolla S, Chandrani P, Choughule A, Pange P, Gupta V, Noronha V, Patil VM, Pramanik R, Kumar S, Nayak SP, Babu S, Shetty R, Kantharaju M, Chinder PS, Korlimarla A, Srinath BS, Prabhash K, Rishi KD, Goswami HM, Veldore VH

JCO Glob Oncol (2023)

Paper

In silico structural analysis of secretory clusterin to assess pathogenicity of mutations identified in the evolutionarily conserved regions

Das L, Shekhar S, Chandrani P, Varma AK

J Biomol Struct Dyn (2023)

Paper

Progesterone modulates the DSCAM-AS1/miR-130a/ESR1 axis to suppress cell invasion and migration in breast cancer

Yadav N, Sunder R, Desai S, Dharavath B, Chandrani P, Godbole M, Dutt A

Breast Cancer Res (2022)

Paper

Integrated proteomics and phosphoproteomics revealed druggable kinases in neoadjuvant chemotherapy resistant tongue cancer

George IA, Sathe G, Ghose V, Chougule A, Chandrani P, Patil V, Noronha V, Venkataramanan R, Limaye S, Pandey A, Prabhash K, Kumar P

Front Cell Dev Biol (2022)

Paper

In vivo tumor immune microenvironment phenotypes correlate with inflammation and vasculature to predict immunotherapy response

Sahu A, Kose K, Kraehenbuehl L, Byers C, Holland A, Tembo T, Santella A, Alfonso A, Li M, Cordova M, Gill M, Fox C, Gonzalez S, Kumar P, Wang AW, Kurtansky N, Chandrani P, Yin S, Mehta P, Navarrete-Dechent C, Peterson G, King K, Dusza S, Yang N, Liu S, Phillips W, Guitera P, Rossi A, Halpern A, Deng L, Pulitzer M, Marghoob A, Chen CJ, Merghoub T, Rajadhyaksha M

Nat Commun (2022)

Paper

Lung cancer with dual EGFR and ALK driver alterations at baseline: a retrospective observational cohort study

Noronha V, Chougule A, Chandrani P, Kaushal RK, Patil VM, Menon N, Kapoor A, Chopade S, Singh A, Shetty O, Dutt A, Banavali S, Prabhash K

Acta Oncol (2022)

Paper

Impact of Molecular Tumor Board on the Clinical Management of Patients With Cancer

Behel V, Noronha V, Choughule A, Shetty O, Chandrani P, Kapoor A, Bondili SK, Bajpai J, Kumar R, Pai T, Bal M, Gurav M, Bapat P, Mittal N, Menon S, Patil V, Menon N, Dutt A, Prabhash K

JCO Glob Oncol (2022)

Paper

Clinical Utility of Liquid Biopsy (Cell-free DNA) Based EGFR Mutation Detection Post treatment Initiation as a Disease Monitoring Tool in Patients With Advanced EGFR-mutant NSCLC

Behel V, Chougule A, Noronha V, Patil VM, Menon N, Singh A, Chopade S, Kumar R, Shah S, More S, Banavali SD, Chandrani P, Prabhash K

Clin Lung Cancer (2022)

Paper

Comprehensive Development and Implementation of Good Laboratory Practice for NGS Based Targeted Panel on Solid Tumor FFPE Tissues in Diagnostics

Chougule A, Jagtap V, Nikam A, Kale S, Nambiar K, Bagayatkar P, Chandrani P, Kaushal R, Noronha V, Patil V, Banavali S, Prabhash K

Diagnostics (Basel) (2022)

Paper

Treatment pattern and outcomes in de novo T790M-mutated non-small cell lung cancer

Panda GS, Noronha V, Shah D, John G, Chougule A, Patil V, Kumar R, Menon N, Singh A, Chandrani P, Mahajan A, Prabhash K

Ecancermedicalscience (2022)

Paper

Fusobacterium nucleatum is associated with inflammation and poor survival in early-stage HPV-negative tongue cancer

Desai S, Dharavath B, Manavalan S, Rane A, Redhu AK, Sunder R, Butle A, Mishra R, Joshi A, Togar T, Apte S, Bala P, Chandrani P, Chopra S, Bashyam MD, Banerjee A, Prabhash K, Nair S, Dutt A

NAR Cancer (2022)

Paper

Systemic Therapy in Thyroid Cancer

Agrawal AK, Noronha V, Patil V, Menon N, Kapoor A, Chougule A, Chandrani P, Prabhash K

Indian J Surg Oncol (2022)

Paper

Landscape of toll-like receptors expression in tumor microenvironment of triple negative breast cancer (TNBC): Distinct roles of TLR4 and TLR8

Roychowdhury A, Jondhale M, Saldanha E, Ghosh D, Kumar Panda C, Chandrani P, Mukherjee N

Gene (2021)

Paper

Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations

Joshi A, Mishra R, Desai S, Chandrani P, Kore H, Sunder R, Hait S, Iyer P, Trivedi V, Choughule A, Noronha V, Joshi A, Patil V, Menon N, Kumar R, Prabhash K, Dutt A

Oncotarget (2021)

Paper

Metabolic rewiring in drug resistant cells exhibit higher OXPHOS and fatty acids as preferred major source to cellular energetics

Salunkhe S, Mishra SV, Ghorai A, Hole A, Chandrani P, Dutt A, Chilakapati M, Dutt S

Biochim Biophys Acta Bioenerg (2020)

Paper

Merkel Cell Polyomavirus in Merkel Cell Carcinoma: Integration Sites and Involvement of the KMT2D Tumor Suppressor Gene

Arora R, Choi JE, Harms PW, Chandrani P

Viruses (2020)

Paper

CytoPred: 7-gene pair metric for AML cytogenetic risk prediction

Salunkhe S, Chandran N, Chandrani P, Dutt A, Dutt S

Brief Bioinform (2020)

Paper

Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a

Sikder S, Kumari S, Kumar M, Sen S, Singhal NB, Chellappan S, Godbole M, Chandrani P, Dutt A, Gopinath KS, Kundu TK

Oncotarget (2019)

Paper

Merkel cell polyomavirus is implicated in a subset of Merkel cell carcinomas, in the Indian subcontinent

Arora R, Rekhi B, Chandrani P, Krishna S, Dutt A

Microb Pathog (2019)

Paper

ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer

Iyer P, Shrikhande SV, Ranjan M, Joshi A, Gardi N, Prasad R, Dharavath B, Thorat R, Salunkhe S, Sahoo B, Chandrani P, Kore H, Mohanty B, Chaudhari V, Choughule A, Kawle D, Chaudhari P, Ingle A, Banavali S, Gera P, Ramadwar MR, Prabhash K, Barreto SG, Dutt S, Dutt A

Int J Cancer (2019)

Paper

Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells

Godbole M, Togar T, Patel K, Dharavath B, Yadav N, Janjuha S, Gardi N, Tiwary K, Terwadkar P, Desai S, Prasad R, Dhamne H, Karve K, Salunkhe S, Kawle D, Chandrani P, Dutt S, Gupta S, Badwe RA, Dutt A

J Biol Chem (2018)

Paper

miR-129-2 mediates down-regulation of progesterone receptor in response to progesterone in breast cancer cells

Godbole M, Chandrani P, Gardi N, Dhamne H, Patel K, Yadav N, Gupta S, Badwe R, Dutt A

Cancer Biol Ther (2017)

Paper

Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases

Upadhyay P, Gardi N, Desai S, Chandrani P, Joshi A, Dharavath B, Arora P, Bal M, Nair S, Dutt A

Oral Oncol (2017)

Paper

Drug-sensitive FGFR3 mutations in lung adenocarcinoma

Chandrani P, Prabhash K, Prasad R, Sethunath V, Ranjan M, Iyer P, Aich J, Dhamne H, Iyer DN, Upadhyay P, Mohanty B, Chandna P, Kumar R, Joshi A, Noronha V, Patil V, Ramaswamy A, Karpe A, Thorat R, Chaudhari P, Ingle A, Choughule A, Dutt A

Ann Oncol (2017)

Paper

Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer

Upadhyay P, Nair S, Kaur E, Aich J, Dani P, Sethunath V, Gardi N, Chandrani P, Godbole M, Sonawane K, Prasad R, Kannan S, Agarwal B, Kane S, Gupta S, Dutt S, Dutt A

Oncotarget (2016)

Paper

TMC-SNPdb: an Indian germline variant database derived from whole exome sequences

Upadhyay P, Gardi N, Desai S, Sahoo B, Singh A, Togar T, Iyer P, Prasad R, Chandrani P, Gupta S, Dutt A

Database (Oxford) (2016)

Paper

Non-typhoidal Salmonella DNA traces in gallbladder cancer

Iyer P, Barreto SG, Sahoo B, Chandrani P, Ramadwar MR, Shrikhande SV, Dutt A

Infect Agent Cancer (2016)

Paper

Integrated genomics approach to identify biologically relevant alterations in fewer samples

Chandrani P, Upadhyay P, Iyer P, Tanna M, Shetty M, Raghuram GV, Oak N, Singh A, Chaubal R, Ramteke M, Gupta S, Dutt A

BMC Genomics (2015)

Paper

NGS-based approach to determine the presence of HPV and their sites of integration in human cancer genome

Chandrani P, Kulkarni V, Iyer P, Upadhyay P, Chaubal R, Das P, Mulherkar R, Singh R, Dutt A

Br J Cancer (2015)

Paper

Coexistence of KRAS mutation with mutant but not wild-type EGFR predicts response to tyrosine-kinase inhibitors in human lung cancer

Choughule A, Sharma R, Trivedi V, Thavamani A, Noronha V, Joshi A, Desai S, Chandrani P, Sundaram P, Utture S, Jambhekar N, Gupta S, Aich J, Prabhash K, Dutt A

Br J Cancer (2014)

Paper

Frequency of EGFR mutations in 907 lung adenocarcioma patients of Indian ethnicity

Chougule A, Prabhash K, Noronha V, Joshi A, Thavamani A, Chandrani P, Upadhyay P, Utture S, Desai S, Jambhekar N, Dutt A

PLoS One (2013)

Paper

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